Study finds LSD decreases brain reactivity to fearful faces

Lysergic acid diethylamide (LSD) reduces activity in the emotion processing centre of the human brain known as the amygdala, according to a study recently published in Translational Psychology.

LSD is a potent psychoactive drug known to alter perception, awareness and emotions by over-activating specialised serotonin receptors in the brain. The need to study the effects of LSD for potential use in research and clinical practise is increasing, because it is thought to reduce anxiety in patients who are diagnosed with a life-threatening illness. Although the basic psychological effects of LSD are understood, data examining the effect of LSD on emotion processing in humans is limited.

A team of scientists from the University of Basel, Switzerland recruited 20 healthy participants (9 males, 11 females) to take part in a double-blind clinical trial that investigated the effects of LSD on emotion processing.

Participants received a small dose of LSD or a placebo before undergoing an fMRI scan to measure their brain activation whilst they carried out a gender identification task using stimuli that displayed a range of human emotion. It was found that participants who had taken LSD had reduced activation of the left amygdala and right medial prefrontal cortex (mPFC) (involved in processing risk and fear) in response to being shown images of fearful faces.

The results suggest that even a small amount of LSD interferes with the activity in brain regions that control emotion processing. More specifically, it was found that LSD produces a selective deficit in the ability to recognise fearful faces. Furthermore, the study found that LSD specifically affected the left amygdala, which previous studies have suggested to be involved in processing negative facial expressions. As mentioned above LSD acts mainly on serotonin receptors which are abundant in the amygdala, which provides a pharmacological explanation for the effect of LSD in this area.

The study also indicated a decrease in activity in the right mPFC which forms part of a neural network with the amygdala involved in emotion processing. This suggests that LSD also decreases the functional connectivity between these two brain regions after being exposed to fearful stimuli.

The results of this study suggest that psychoactive substances such as LSD have the potential to be  used as a treatment for conditions such as depression and anxiety because it can reduce the perception of negative emotions.

Original Source: www.psypost.org

Facebook Comments

59 Comments

  1. yeezy sneakers September 19, 2017 Reply
  2. kyrie shoes September 19, 2017 Reply
  3. yeezy boost 350 September 20, 2017 Reply
  4. cartier love bracelet September 20, 2017 Reply
  5. yeezys September 21, 2017 Reply
  6. adidas ultra boost September 21, 2017 Reply
  7. adidas nmd runner September 21, 2017 Reply
  8. hogan outlet online September 22, 2017 Reply
  9. adidas ultra boost September 22, 2017 Reply
  10. michael kors outlet September 22, 2017 Reply
  11. adidas nmd r1 September 23, 2017 Reply
  12. tory burch shoes September 23, 2017 Reply
  13. adidas ultra boost September 24, 2017 Reply
  14. adidas tubular September 24, 2017 Reply
  15. yeezy boost 350 September 25, 2017 Reply
  16. golden goose outlet September 25, 2017 Reply
  17. yeezy boost September 26, 2017 Reply
  18. retro jordans September 26, 2017 Reply
  19. adidas nmd September 27, 2017 Reply
  20. nike dunks September 27, 2017 Reply
  21. yeezy September 28, 2017 Reply
  22. air jordan shoes September 28, 2017 Reply
  23. adidas nmd runner September 28, 2017 Reply
  24. cheap jordans September 29, 2017 Reply
  25. yeezys September 29, 2017 Reply
  26. yeezy boost 350 v2 September 30, 2017 Reply
  27. yeezy boost 350 October 1, 2017 Reply
  28. jordan shoes October 1, 2017 Reply
  29. adidas yeezy boost October 2, 2017 Reply
  30. pandora jewelry October 3, 2017 Reply
  31. yeezy boost October 4, 2017 Reply
  32. cheap mlb jerseys October 4, 2017 Reply
  33. yeezy boost 350 v2 October 5, 2017 Reply
  34. longchamp handbags October 6, 2017 Reply
  35. nmd October 7, 2017 Reply
  36. adidas ultra October 8, 2017 Reply
  37. Kanye West shoes October 9, 2017 Reply
  38. jordan retro October 9, 2017 Reply
  39. nmd October 10, 2017 Reply
  40. authentic jordans October 10, 2017 Reply
  41. adidas yeezy boost October 10, 2017 Reply
  42. yeezy boost October 11, 2017 Reply
  43. yeezy boost 350 October 11, 2017 Reply
  44. tory burch shoes October 11, 2017 Reply
  45. yeezy shoes October 12, 2017 Reply
  46. pandora bracelet October 12, 2017 Reply
  47. yeezy October 13, 2017 Reply
  48. longchamp October 13, 2017 Reply
  49. yeezy boost 350 v2 October 13, 2017 Reply
  50. lebron 13 October 14, 2017 Reply
  51. nmd uk October 14, 2017 Reply

Leave a Reply